Andy Clegg is a Professor of Geriatric Medicine, University of Leeds and Honorary Consultant Geriatrician, Bradford Royal Infirmary, Director of the Global Ageing Research Trialist (ART) collaborative, and Co-Director for Health Data Research UK (HDRUK) North. His expertise is in frailty, medicines optimisation, prognostic modelling and evaluation of interventions using trial-based methods and routine data. He led the development, validation and national implementation of the multi award-winning and NICE-recommended electronic frailty index (eFI) using data from around 1M UK patients contained in the ResearchOne and THIN primary care research databases, with major impact on NHS policy, including the NHS Long Term Plan.
He is the lead for the NIHR ARC Yorkshire & Humber Improving Care for Older People with Frailty theme, Chief Investigator (CI) for an NIHR Programme Grant to optimise and evaluate personalised care planning for older people with frailty (PROSPER) and CI for the NIHR HTA-funded Home- based Extended Rehabilitation for Older People (HERO) trial. Professor Clegg is also CI for the Community Ageing Research 75+ (CARE 75+) multi-site cohort study to investigate frailty, disability and quality of life trajectories in older age, and evaluate interventions to improve outcomes using a novel ‘trial within cohort’ (TWiCs) design.
Professor Clegg is a current member of the MRC Ageing Research Steering Group, supporting development of future activities in ageing research. He is also co-lead for the NIHR National Ageing, Dementia and Frailty Priority Theme, supporting national implementation of prioritised interventions into routine practice, and co-investigator with the NIHR Policy Research Unit for Older People and Frailty. He is a current member of the NICE Falls Prevention Guideline Development Group. Previous roles include as a member of the NICE Multimorbidity Guideline Development Group, NICE Delirium Guideline Development Group, and joint Centre for Perioperative Care & British Geriatrics Society guideline on Perioperative Care for Older People with Frailty.
Areas that he may include in his talks are findings from a major network meta-analysis of community-based complex interventions for older people, results from the HERO RCT of extended rehabilitation, and from his prognostic modelling work (eFI+/eFI2). He may also discuss his evidence synthesis work, including individual participant data meta-analysis, which is being explored through the Ageing Research Trialists collaborative.